Current Research 

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1. Multicentre pain research project

Pain sources in chronic pain patients attending multicentre pain clinics: a retrospective study.

Alena-Mihaela Boros, Wei Lan, Dominic Harmon

 

2. An up to date survey of acute pain services in multiple centres in Ireland.

Danial Hussein, Wei Lan

 

3.The impact of COVID-19 on chronic pain patients in multidisciplinary services. 

Danial Hussein, Wei Lan

 

4. An audit of the management and outcomes of patients with Complex Regional Pain Syndrome (CRPS) attending pain clinic in Cork- a single centre experience.

Alanna McMullin, Wei Lan

 

 

 

Contributor Pain and Anaesthesia Research Centre, Barts Health NHS Trust, UK.

 

Multicentre double blind randomised controlled trial to assess the clinical and cost effectiveness of facet injections in selected patients with non-specific low back pain: a feasibility study.

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Peer review Publications 

1).  The effect of clomethiazole on plasma concentrations of IL-6, IL-8, IL-1β, TNF-α  

       and neutrophil adhesion molecule expression during experimental extracorporeal  

       circulation.

       D Harmon, E Coleman, C Marshall, W Lan, G Shorten. Anesth Analg 2003; 97(1): 

       13-8.                                                                                                                

 

2).  The effect of Lidocaine on Neutrophil and Endothelila Adhesion Molecule 

       Expression Induced by Plasma Obtained During Tourniquet-Induced Ischaemia

       Reperfusion.

       W Lan, D Harmon, JH Wang, G Shorten, P Redmond. Eur J Anaesth 2004;

       21:11:892-897.

 

3).   The effect of lidocaine on neutrophil CD11b/CD18, endothelial ICAM-1 expression 

       and IL-1 β concentrations associated with in-vitro hypoxia-reoxygenation.

       W Lan, D Harmon, JH Wang, G Shorten, P Redmond.  Eur J Anaesth 2004;  

       21:12:967-972.

 

4).   The effect of aprotinin on hypoxia-reoxygenation –induce changes in neutrophil and 

       endothelial function.

       D Harmon, W Lan, G Shorten.  Eur J Anaesth 2004; 21:12:973-979.

 

5).  Effect of aprotinin on in vitro cerebral endothelial ICAM-1 expression induced by

       astrocyte-conditioned medium.

       D Harmon, K Ghori, W Lan, G shorten.  Eur J Anaesth 2005; 22:4:277-282.

 

6).  Activated endothelial IL-1, IL-6, IL-8 concentrations and ICAM-1 expression are

       attenuated by lidocaine.

       W Lan, D Harmon, JH Wang, G Shorten, P Redmond.  Anesth Analg 2005; 100 (2): 

       409-412.

 

7).  The effect of midazolam on cerebral endothelial (P-selectin and ICAM-1) adhesion

        molecule expression during hypoxia-reperfusion injury in vitro.

       K Ghori, D Harmon, W Lan, P Seigne, F Walsh, GD Shorten.  Eur J Anaesth  2008;  

       25(3): 206-10.

 

8). Ultrasound Guided Temporomandibular Joint Injection Technique.

      W Lan, D Harmon.  Irish J Medical Science 2009;178:S86

 

9).  Attention  (mindfulness awareness) and chronic pain. 

      H McElligott, J O’Driscoll, W Lan, D Harmon.   Mesentry and Peritoneum 2018  

       AB210. 18

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10).  Uncertainty and chronic pain.  

        R McGovern, D Edgeworth, M Hashim, A Duggan, F Irwin, W Lan, D Harmon.  

       Mesentry and Peritoneum 2018 AB 213.  26.

 

 

 

Letter to the editor

 

Effects of systemic local anesthetics on perioperative ischemia reperfusion may be beneficial.

D Harmon, W Lan. Anesth Analg 2003; 96: 629

 

 

 

Abstracts

 

1). Attention (mindfulness awareness) and chronic pain.

    W Lan, H McElligott, J O’ Driscoll, D Harmon. Mesentry and Peritoneum 2018

    AB210. 18.

2). Uncertainty and chronic pain.

     W Lan, R McGovern, D Edgeworth, M Hashim, A Duggan, F Irwin, D Harmon

      Mesentry and Peritoneum 2018 AB213. 26.

3).  Assessment of patient concerns prior to pain relief interventions.

      W Lan, F Irwin, AM Kiernan, D Harmon. Mesentry and Peritoneum 2018 AB221.  

      244.

 

4).  The effect of lidocaine on neutrophil CD11b/CD18, endothelial ICAM-1 expression   

       and IL-1 β concentrations associated with in-vitro hypoxia-reoxygenation.

       W Lan, D Harmon, JH Wang, G Shorten, P Redmond.  Eur J Anaesth 2004;A491.

 

5).  Activated Endothelial IL-1, IL-6, IL-8 concentrations and ICAM-1 expression are 

       attenuated by lidocaine.

      W Lan, D Harmon, JH Wang, G Shorten, P Redmond.  Eur J Anaesth 2004;A431.

 

6).  The Effects of Lidocaine on Neutrophil and Endothelila Adhesion Molecule  

       Expression Induced by Plasma Obtained During Tourniquet Induced Ischaemia

       Reperfusion.

      W Lan, D Harmon, JH Wang, K Ghori, G Shorten.  Anesthesiology 2003;99:A1054.

 

7).  Aprotinin and Hypoxia Reoxygenation Changes in Endothelial Function.

       D Harmon, W Lan, G Shorten.  Anesthesiology 2003;A869.

 

8).  Inflammatory Activation of Mouse Brain Endothelial Cells by Hypoxic Astrocytes in   

      Vitro Is Decreased by Aprotinin.

      D Harmon, K Ghori, W Lan, G Shorten.  Anesthesiology 2003;A854.

 

9).  The Effects of Midazolam on Hypoxia/Reoxygenation Expression of Cerebral  

       Endothelial  (P-selectin & ICAM-1) and Neutrophils (CD11/CD18) Adhesion  

       Molecules and IL-1β Concentrations in Vitro.

       K Ghori, D Harmon, W Lan, F Walsh, P Seigne, G Shorten.  Anesthesiology  

       2003;A874.

 

10). The Protective Effect of Midazolam on Inflammatory Activation of Brain  

        Endothelial Cells by Hypoxic Astrocytes In Vitro.
       K Ghori, D Harmon, W Lan, F Walsh, P Seigne, G Shorten. Anesthesiology  

       2003;A817.

 

11).  Anti-Inflammatory Effect of Midazolam: Inhibition of p38 Mitogen Activated

        Protein Kinase (MAPK) in Human Neutrophils.

       K Ghori, D Harmon, W Lan, G Shorten. Anesthesiology 2003; A854.

 

12). Aprotinin and Anoxia Reoxygenation Changes in Neutrophil Function.

        D Harmon, W Lan, K Ghori, G Shorten. Anesthesiology 2002; 96: A725.

 

 

 

Presentations

 

1).  Obstetric patients admissions in general intensive care unit: a 2 year retrospective

      study in a centralised care institute in Ireland. 

      W Lan, F Walsh.

      Irish Society of Obstetric Anaesthetists Annual Meeting. College of Anaesthetists of    

      Ireland.  Dublin, Ireland.   December, 2014.

 

2).  A case report: Unilateral Horner’s Syndrome Following Epidural Anaesthesia For Labour   

     And Caesarean Section.

      W Lan, M Duggan.   

      Sylvester O’Halloran Surgical Scientific Meeting, University Of Limerick, Ireland,   

      March, 2012

 

3).  Ultrasound-Guided Temporomandibular Joint Injection Technique.

     W Lan, D Harmon, G Shorten.

     Sylvester O’Halloran Surgical Scientific Meeting, University of Limerick, Ireland,

     March, 2009.

 

4).  The effects of lidocaine on neutrophil and endothelial adhesion molecule expression  

      induced by plasma obtained during tourniquet induced ischaemia reperfusion

      W Lan, D Harmon, G Shorten.

      5th Current Controversies in Anaesthesia & Peri-Operative Medicine, Dingle, Co   

      Kerry, Ireland, March 2003.

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5).  The effect of clomethiazole on plasma concentrations of IL-6, IL-8, IL-1β, TNF-α   

       and adhesion molecule expression during experimental extracorporeal

       circulation.

       D Harmon, E Coleman, C Marshall, W Lan, G Shorten.

       South of Ireland Annual Scientific Meeting 2002. Registrar Prize Winner.

 

 

Poster Presentations

 

1).  The effect of lidocaine on neutrophil CD11b/CD18, endothelial ICAM-1 expression

       and IL-1 β concentrations associated with in-vitro hypoxia-reoxygenation.

      W Lan, D Harmon, JH Wang, G Shorten, P Redmond. 

      European Society of Anaesthesiologists Annual meeting, Lisbon, Portugal, June,  

      2004.

 

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2).  Activated Endothelial IL-1, IL-6, IL-8 concentrations and ICAM-1 expression are  

       attenuated by lidocaine.

      W Lan, D Harmon, JH Wang, G Shorten, P Redmond. 

      European Society of Anaesthesiologists Annual meeting, Lisbon, Portugal, June,  

      2004.

 

3).  The effects of lidocaine on neutrophil and endothelial adhesion molecule expression  

       induced by plasma obtained during tourniquet induced ischaemia reperfusion.  

      W Lan, D Harmon, JH Wang, G Shorten.

      American Society of Anesthesia Annual Meeting, San Francisco, May, 2003.

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4).  The effect of lidocaine on neutrophil CD11b/CD18, endothelial ICAM-1 expression   

       and IL-1 β concentrations associated with in-vitro hypoxia-reoxygenation.

       W Lan, D Harmon, JH Wang, G Shorten. 

       5 th  Current Controversies in Anaesthesia & Peri-Operative Medicine,  Dingle,   

       Kerry, Ireland, March, 2003.

 

5).  Aprotinin and Hypoxia Reoxygenation Changes in Endothelial Function.

       D Harmon, W Lan, G Shorten.

       American Society of Anesthesia Annual Meeting, San Francisco, September, 2003.

 

6).  Inflammatory Activation of Mouse Brain Endothelial Cells by Hypoxic Astrocytes in  

      Vitro Is Decreased by Aprotinin.

      D Harmon, K Ghori, W Lan, G Shorten.

      American Society of Anesthesia Annual Meeting, San Francisco, September, 2003.

 

7).  The Effects of Midazolam on Hypoxia/Reoxygenation Expression of Cerebral  

       Endothelial (P-selectin & ICAM-1) and Neutrophils (CD11/CD18) Adhesion  

       Molecules and IL-1β Concentrations in Vitro.

       K Ghori, D Harmon, W Lan, F Walsh, P Seigne, G Shorten. 

       American Society of Anesthesia Annual Meeting, San Francisco, September, 2003.

 

8).  The Protective Effect of Midazolam on Inflammatory Activation of Brain Endothelial  

       Cells by Hypoxic Astrocytes In Vitro.
      K Ghori, D Harmon, W Lan, F Walsh, P Seigne, D Shorten. 

       American Society of Anesthesia Annual Meeting, San Francisco, September, 2003.

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9).  Aprotinin and Anoxia Reoxygenation Changes in Neutrophil Function.

      D Harmon, W Lan, K Ghori, G Shorten.

     American Society of Anesthesia Annual Meeting, Florida, April,2002.